Dr Aidan Cole

Qualifications

MB BCH BAO

Queen’s University of Belfast 2003

Diploma in Oncology

Institute of Cancer Research 2008

Doctor of Philosophy (PhD)

Queen’s University Belfast 2014

Post Graduate Certificate of Education (Clinical Education-PGCE)

Queen’s University 2016

Additional Training

Advanced Radiotherapy Fellowship, Peter MacCallum Cancer Centre Melbourne 2016-2017

Professional bodies (Positions held in last 3 years)

Fellow of the Royal College of Radiologists of London FRCR 2015

Member of the Royal College of Physicians of Edinburgh (MRCP) 2007

Publications

CT-based Radiomics for Risk Stratification in Prostate Cancer. Osman S, Leijenaar RT, Cole AJ, Lyons CA, Hounsell AR, Prise KM, O’Sullivan JM, Lambin P, McGarry CK, Jain S. Published June 2019 International Journal of Radiation, Physics and Biology. https://doi.org/10.1016/j.ijrobp.2019.06.2504

Systematic Endobronchial Ultrasound-Transbronchial Needle Aspiration improves radiotherapy planning in non-small cell lung cancer. Cole AJ, Turgeon GA, Hardcastle N, Kron T, Ball D, Jennings B, Irving L, Steinfort D, Siva S. ERJ Open Research 2019 5: 00004-2019; DOI: 10.1183/23120541.00004-2019

A pilot study of patient reported outcomes evaluating treatment related symptoms and quality of life for men receving high dose rate brachytherapy combined with hypo-fractionated radiotherapy or hypofractionated radiotherapy alone for the treatment of prostate cancer. Crowther K, Cole AJ, Shiels, P, Jain S, Shepherd P, Mitchell D. Technical Innovations and Patient Support in Radiation Oncology 2019 (9) 18-25

What FDG-PET response-assessment method best predicts survival after curative-intent chemoradiation in non-small cell lung cancer (NSCLC) EORTC, PERCIST, Peter Mac or Deauville criteria? Turgeon, Guy-Anne; Iravani, Amir; Akhurst, Tim; Beaulieu, Alexis; Callahan, Jason W; Bressel, Mathias; Cole, Aidan J; Everitt, Sarah; Siva, Shankar; Hicks, Rodney J; Ball, David L; Mac Manus, Michael P.In: The Journal of Nuclear Medicine, 20.07.2018, p. 1-42.

Blyth, B, Cole AJ, MacManus M, Martin, OA. Radiation therapy-induced metastasis: radiobiology and clinical implications. 2017. Clinial and Experimental Metastasis. 2017 Nov 20. doi: 10.1007/s10585-017-9867-5.

Alderdice M, Dunne PD, Cole AJ, O’Reilly PG, McArt DG, Bingham V, Marc-Aurel Fuchs, McQuaid S, Loughrey MB, Murray GI, Samuel LM, Lawler M, Wilson RH, Salto-Tellez, Coyle VM. Natural killer-like signature observed post therapy in locally advanced rectal cancer is a determinant of pathological response and improved survival. 2017 Modern Pathology 30, 1287-1298

Butterworth KT, McMahon SJ, McKee JC, Patel G, Ghita M, Cole AJ, McGarry CK, O’Sullivan JM, Hounsell AR, Prise KM. Time and Cell Type Dependency of Survival Responses in Co-Cultured Tumor and Fibroblast Cells after Exposure to Modulated Radiation Fields. Radiation Research. 2015 May 14. 183(6), 656-664. DOI: 10.1667/RR13992.1

O'Connell B, Irvine DM, Cole AJ, Hanna GG, McGarry CK. Optimizing geometric accuracy of four dimensional CT scans acquired using the wall and couch mounted Varian Real-Time Position Management camera systems. Br J Radiol. 2014 Dec 3:20140624.

Cole AJ, Hanna GG. Sterotactic radiotherapy for early stage lung cancer. 2015 Ulster Medical Journal. 84(1) 69-70

Cole AJ, O'Hare JM, McMahon SJ, McGarry CK, Butterworth KT, McAleese J, Jain S, Hounsell AR, Prise KM, Hanna GG, O'Sullivan JM. Investigating the Potential Impact of Four-dimensional Computed Tomography (4DCT) on Toxicity, Outcomes and Dose Escalation for Radical Lung Cancer Radiotherapy. Clin Oncol (R Coll Radiol). 2014 Mar;26(3):142-50. doi: 10.1016/j.clon.2013.11.024.

Cole AJ, Hanna GG, Jain S, O'Sullivan JM. Motion management for radical radiotherapy in non-small cell lung cancer. Clin Oncol (R Coll Radiol). 2014 Feb;26(2):67-80. doi: 10.1016/j.clon.2013.11.001.

Hyland WB, McMahon SJ, Butterworth KT, Cole AJ, King RB, Redmond KM, Prise KM, Hounsell AR, McGarry CK. Investigation into the radiobiological consequences of pre-treatment verification imaging with megavoltage X-rays in radiotherapy. Br J Radiol 2014, Apr 87(1036).

Cole AJ, McGarry CK, Butterworth KT, McMahon SM, Hounsell AR, Prise KM, O’Sullivan JM. Investigating the influence of respiratory motion on the radiation induced bystander effect in modulated radiotherapy. 2013. Phys Med Biol 7;58(23) 8311-22

King RB, Hyland WB, Cole AJ, Butterworth KT, McMahon SJ, Redmond KM, Trainer C, Prise KM, McGarry CK, Hounsell AR. An in vitro study of the radiobiological effects of flattening filter free radiotherapy treatments. 2013. Phys Med Biol 2013, 7 (58) N83-94.

Cole AJ, McGarry CK, Butterworth KT, Prise KM, O’Sullivan JM, Hounsell AR. Development of a novel experimental model to investigate radiobiological implications of respiratory motion in advanced radiotherapy. 2012 Phys Med Biol, 57(22) N411-20

Cole AJ, Pridee NR, McAleer JJ. Chemotherapy causes cancer! A case report of therapy related acute myeloid leukaemia in early stage breast cancer. 2013. Ulster Med Journal 82(2) 97-99

Treatments and areas of interest

• Radiotherapy for localised prostate cancer
• Chemotherapy
• Radionuclide therapy
• Hormone therapy
• Bone therapies in prostate cancer
• Clinical trials and research into prostate cancer
• Stereotactic Radiotherapy (SABR/SBRT)
• Stereotactic Radiotherapy for Oligometastatic Disease (Breast/Colorectal/Lung Cancer)
• Post-prostatectomy radiotherapy
• Active Surveillance